MS / M.Phil Microbiology and Molecular Genetics

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MMG 7634: BIOPHYSICS AND COMPUTATIONAL BIOLOGY

Overview

THEORY: Architecture and Physical Properties of Proteins, Introduction: Governor of biological phenomena, Protein, Variety and similarity in protein architecture, 3D structure prediction, Symmetry in supramolecules, Membrane protein structure, Protein folding and the physical principles, Protein dynamic features: Complex and dynamic system, protein. Observation of dynamic properties by molecular simulation, Dynamics from protein crystallography, Solution X-ray and neutron scattering, Molecular motions monitored by NMR spectroscopy. Behaviors of genes-dynamic DNAs, Methods in Structural Biology, Structural Biology Software Database - NIH resource, at UIUC Bioinformatics software Biocatalog - at EBI.
PRACTICAL: Data base analysis, Data retrieving, Bioinformatic soft wars regarding crystallography.


Credit hours/ Marks:- 3+1

1. Architecture and Physic al Properties of Proteins, 2005, Edited by H. Nakamura and F. Arisaka, Published: Biophysical Society of Japan.
2. Biological Physics : Energy, Information, Life, 2003. Philip Nelson
ISBN: 0716743728, Publisher: W. H. Freeman
3. D. Schomburg and U. Lessel, Bioinformatics: From Nucleic Acids and Proteins to Cell Metabolism. Wiley. John & Sons, 1995.

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